Lero, talandira funso losangalatsa kuchokera ku Velentium Medical, kampani yomwe ikufunsa za momwe timapezera mawaya a maginito ogwirizana ndi zinthu zachilengedwe ndi mawaya a Litz, makamaka opangidwa ndi siliva kapena golide, kapena njira zina zotetezera zomwe zimagwirizana ndi zinthu zachilengedwe. Chofunika ichi chikugwirizana ndi ukadaulo wochapira opanda zingwe wa zida zachipatala zomwe zingabzalidwe.
Tianjin Ruiyuan Electrical Equipment Co., Ltd. yakhala ikukumana ndi mafunso otere kale ndipo yapatsa makasitomala mayankho apamwamba kwambiri. Ruiyuan Laboratory yachitanso kafukufuku wotsatirawu pa golide, siliva, ndi mkuwa ngati zinthu zomwe zingathe kubzalidwa m'nthaka:
Mu zipangizo zachipatala zomwe zimayikidwa m'thupi, kugwirizana kwa zinthu kumadalira momwe zimagwirira ntchito ndi minofu ya anthu, kuphatikizapo zinthu monga kukana dzimbiri, chitetezo cha mthupi, komanso poizoni. Golide (Au) ndi siliva (Ag) nthawi zambiri zimaonedwa kuti zimagwirizana bwino ndi zinthu zina, pomwe mkuwa (Cu) umagwirizana bwino ndi zinthu zina, pazifukwa izi:
1. Kugwirizana kwa Golide (Au)
Kusagwira ntchito kwa mankhwala: Golide ndi chitsulo chabwino chomwe sichimasungunuka kapena kuwononga chilengedwe ndipo sichitulutsa ma ayoni ambiri m'thupi.
Kuchepa kwa chitetezo chamthupi: Golide nthawi zambiri samayambitsa kutupa kapena kukana chitetezo chamthupi, zomwe zimapangitsa kuti chikhale choyenera kuikidwa m'thupi kwa nthawi yayitali.
2. Kugwirizana kwa Siliva (Ag)
Mphamvu yoletsa mabakiteriya: Ma ayoni asiliva (Ag⁺) ali ndi mphamvu yoletsa mabakiteriya ambiri, motero amagwiritsidwa ntchito kwambiri mu ma implants afupiafupi (monga ma catheter ndi mabala ophimba).
Kutulutsa koyenera: Ngakhale kuti siliva imatulutsa ma ayoni ochepa, kapangidwe koyenera (monga nano-silver coating) kangachepetse poizoni, kamakhala ndi mphamvu zotsutsana ndi mabakiteriya popanda kuwononga kwambiri maselo a anthu.
Kuopsa kwa poizoni: Kuchuluka kwa ayoni asiliva kungayambitse poizoni wa cytotoxicity, choncho ndikofunikira kuwongolera mosamala mlingo ndi kuchuluka kwa kutulutsidwa kwa mankhwala.
3. Kugwirizana kwa Mkuwa (Cu)
Kuchuluka kwa mankhwala: Mkuwa umasungunuka mosavuta m'thupi (monga kupanga Cu²⁺), ndipo ma ayoni a mkuwa omwe amatulutsidwa amayambitsa ma free radical reaction, zomwe zimapangitsa kuti maselo awonongeke, DNA isweke, komanso mapuloteni asinthe.
Mphamvu yolimbikitsa kutupa: Ma ioni a mkuwa amatha kuyambitsa chitetezo chamthupi, zomwe zimayambitsa kutupa kosatha kapena fibrosis ya minofu.
Kuopsa kwa ubongo: Kuchuluka kwa mkuwa (monga matenda a Wilson) kungawononge chiwindi ndi dongosolo lamanjenje, kotero sikoyenera kuikidwa m'thupi kwa nthawi yayitali.
Kugwiritsa ntchito kwapadera: Mphamvu ya mkuwa yolimbana ndi mabakiteriya imalola kuti igwiritsidwe ntchito pazida zamankhwala zazifupi (monga zophimba pamwamba pa antibacterial), koma kuchuluka kwa kutulutsa kuyenera kulamulidwa mosamala.
Chidule Chachikulu
| Makhalidwe | Golide(a)AU） | Siliva (Ag) | Mkuwa (Cu) |
| Kukana dzimbiri | Wamphamvu kwambiri (wosagwira ntchito) | Yapakatikati (Kutulutsa pang'onopang'ono kwa Ag+) | Yofooka (Kutulutsa kosavuta kwa Cu²+) |
| Chitetezo chamthupi chimayankha | Pafupifupi palibe | Nthawi Yochepa (Nthawi Yoyenera Kulamulira) | Wapamwamba (Woyambitsa kutupa) |
| Kuopsa kwa Ctotoxicity | Palibe | Yapakatikati-yapamwamba (Zimatengera kuchuluka kwa shuga) | Pamwamba |
| Ntchito zazikulu | Ma electrode/ma prostheses okhazikika kwa nthawi yayitali | Ma implants a nthawi yochepa oletsa mabakiteriya | Zosowa (Zimafuna chithandizo chapadera) |
Mapeto
Golide ndi siliva ndi omwe amakondedwa kwambiri pa zinthu zoyikiramo mankhwala chifukwa chakuti sizingawononge kwambiri komanso sizingasinthe momwe zimakhalira, pomwe mankhwala ndi poizoni wa mkuwa zimalepheretsa kugwiritsidwa ntchito kwake m'zinthu zoyikiramo kwa nthawi yayitali. Komabe, kudzera mu kusintha kwa pamwamba (monga oxide coating kapena alloying), mphamvu ya mkuwa yolimbana ndi mabakiteriya ingagwiritsidwenso ntchito pang'ono, koma chitetezo chiyenera kuyesedwa mosamala.
Nthawi yotumizira: Julayi-18-2025
